Beilstein J. Org. Chem.2019,15, 1822–1828, doi:10.3762/bjoc.15.176
, Institute of Molecular Sciences, UMR-CNRS 5255, 351 cours de la libération, Talence, 33405 Cedex, France 10.3762/bjoc.15.176 Abstract Four-component coupling reactions between xanthogenates, alkenes, CO, and sulfonyloximeethers were studied. In the presence of hexabutylditin, working as a propagating
functionalities, have the potential for further elaboration.
Keywords: CO; multicomponent reaction; radicals; sulfonyloximeethers; xanthogenates; Introduction
Multicomponent reactions constitute a powerful and highly efficient tool in organic synthesis to build up intricate compounds from simple molecules in
/acceptor type C1 synthons [6][7][8][9][10][11][12][13][14][15]. In this context, sulfonyloximeethers are powerful acceptors of type C1 synthon [8][16][17], which terminates the multicomponent reaction by a β-scission of RSO2 radicals [18][19][20]. Recently, one of us reported on a three-component radical
PDF
Graphical Abstract
Scheme 1:
Concept: Alkene difuctionalization by four-component radical reaction using xanthates, alkenes, CO ...